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Patients were randomized 3:2 to receive a loading dose of 400 mg followed by 200 mg of ANDEMBRY monthly (n=39) or volume matched placebo monthly (n=25) subcutaneously.
https://newsroom.csl.com/2025-06-16-U-S-Food-and-Drug-Administration-Approves-CSLs-ANDEMBRY-R-garadacimab-gxii-,-the-Only-Prophylactic-Hereditary-Angioedema-HAE-Treatment-Targeting-Factor-XIIa-with-Once-Monthly-Dosing-for-All-Patients-From-the-Start -
TOVs solely related to over-the-counter medicines
https://www.csl.com/-/media/shared/documents/cslviforireland_method_2024.pdf -
ToVs solely related to over-the-counter medicines - ToVs excluded from the scope of the EFPIA Disclosure Code, such as informational and educational materials, items of medical utility, food and beverage, medical samples - Fees charged by logistics agencies assisting in organising travel and meetings
https://www.csl.com/-/media/shared/documents/vifor-disclosures/tov/2024_methodologicalnote_switzerland_draft.pdf -
ToVs solely related to over-the-counter medicines - ToVs excluded from the scope of the EFPIA Disclosure Code, such as informational and educational materials, items of medical utility, food and beverage, medical samples - Fees charged by logistics agencies assisting in organising travel and meetings
https://www.csl.com/-/media/shared/documents/vifor-disclosures/tov/2023_methodologicalnote_switzerland_20240626.pdf -
TOVs solely related to over-the-counter medicines
https://www.csl.com/-/media/shared/documents/vifor-disclosures/methodological-notes/cslviforireland_method_2023_.pdf -
ToVs solely related to over-the-counter medicines - ToVs excluded from the scope of the EFPIA Disclosure Code, such as informational and educational materials, items of medical utility, food and beverage, medical samples - Fees charged by logistics agencies assisting in organising travel and meetings
https://www.csl.com/-/media/shared/documents/vifor-disclosures/methodological-notes/methodological-note_2022_ch.pdf